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<blockquote data-quote="Nelson Vergel" data-source="post: 3511" data-attributes="member: 3"><p>There is controversy about the need to watch for high tyramine foods while on oral selegiline since you can have a dangerous hypertensive crisis (high blood pressure spike)</p><p><a href="http://www.mc.vanderbilt.edu/documents/neurology/files/Tyramine%20Menu%20Book%2006227101.pdf" target="_blank">http://www.mc.vanderbilt.edu/documents/neurology/files/Tyramine Menu Book 06227101.pdf</a></p><p></p><p>For those with insurance, the selegiline patch (EMSAM) is approved for depression.</p><p></p><p>In February 2006 the US Food and Drug Administration approved Emsam (selegiline), the first transdermal patch for use in treating major depression. The once a day patch works by delivering selegiline through the skin and into the bloodstream. Emsam can be used without the dietary restrictions that are needed for all oral MAO inhibitors that are approved for treating major depression, although the FDA requires warnings concerning dietary restrictions for the 9 and 12 mg doses due to theoretical concerns not supported by any reports of adverse events. It comes in three sizes that deliver 6, 9, or 12 mg of selegiline per 24 hours. The patch is a matrix containing three layers consisting of a backing, an adhesive drug layer, and a release liner that is placed against the skin.</p><table class='post-table class: fact, width: 700' style='width: 100%'><tr><td></td></tr></table></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 3511, member: 3"] There is controversy about the need to watch for high tyramine foods while on oral selegiline since you can have a dangerous hypertensive crisis (high blood pressure spike) [URL='http://www.mc.vanderbilt.edu/documents/neurology/files/Tyramine%20Menu%20Book%2006227101.pdf']http://www.mc.vanderbilt.edu/documents/neurology/files/Tyramine Menu Book 06227101.pdf[/URL] For those with insurance, the selegiline patch (EMSAM) is approved for depression. In February 2006 the US Food and Drug Administration approved Emsam (selegiline), the first transdermal patch for use in treating major depression. The once a day patch works by delivering selegiline through the skin and into the bloodstream. Emsam can be used without the dietary restrictions that are needed for all oral MAO inhibitors that are approved for treating major depression, although the FDA requires warnings concerning dietary restrictions for the 9 and 12 mg doses due to theoretical concerns not supported by any reports of adverse events. It comes in three sizes that deliver 6, 9, or 12 mg of selegiline per 24 hours. The patch is a matrix containing three layers consisting of a backing, an adhesive drug layer, and a release liner that is placed against the skin. [TABLE=class:-fact,-width:-700][TR][TD] [/TD][/TR][/TABLE] [/QUOTE]
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