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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
4 Months In - No Improvements - Major E2 Issues - Switching to Defy
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<blockquote data-quote="riverside" data-source="post: 58040" data-attributes="member: 14064"><p>I am 4 months in with TRT and have yet to feel/experience any benefits. Please, please look at these labs and let me know your thoughts. And let me know if you have any questions. I am moving to Defy and have my first consult with Dr. Saya in early January. My doctor now is recommending I increase my AI dose to .5mg every day and I am worried about doing so but I still have high E2 after 6 weeks of .5mg EOD. Should I increase or wait until I discuss with Defy?</p><p></p><p><strong><span style="color: #00000A">Pre TRT:</span></strong></p><p><span style="color: #00000A">Total T = 193 ng/dL 241-827</span></p><p><span style="color: #00000A">Free T = 3.50 ng/dL 3.70-23.28</span></p><p><span style="color: #00000A">SHBG = 33.2 nmol/L 11.0-57.0</span></p><p><span style="color: #00000A">E2 = 2.0 μg/24hrs 0.8 – 7.0</span></p><p><span style="color: #00000A">FSH = 0.9 [IU]/L 1.4 - 18.1 mIU/mL</span></p><p><span style="color: #00000A">LH = 1.3 [IU]/L 1.5 - 8.1 mIU/mL</span></p><p><span style="color: #00000A">DHT = 1.6μg/24hrs 3–16</span></p><p><span style="color: #00000A">TSH = 1.020 uIU/mL 0.350-5.500</span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"><strong>6 Weeks of 70mg E3.5D Test-C, 200IU HCG EOD:</strong></span></p><p><span style="color: #00000A">Testosterone Total - 712 ng/dL 240 - 950 ng/dL</span></p><p><span style="color: #00000A">Testosterone, Free - 173.9 pg/mL pg/mL</span></p><p><span style="color: #00000A">SHBG - 20 nmol/L 10 - 57 nmol/L</span></p><p><span style="color: #00000A">Estradiol (E2) - 63 H pg/mL 10-40</span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"><strong>Switched to EOD injections of 40mg Test-C:</strong></span></p><p><span style="color: #00000A">Estradiol (E2) - 100 H < or = 29 pg/ml</span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"><strong>Dr added AI. After 2 weeks of .25 Anastrazole EOD:</strong></span></p><p><span style="color: #00000A"><strong></strong>Estradiol (E2) - 33 H < or = 29 pg/ml</span></p><p><span style="color: #00000A">Total T - 519 250-827 ng/dL</span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"><strong>Dr changed AI to .5mg EOD and bumped Test-C to 45mg EOD. Labs after 4 weeks:</strong></span></p><p><span style="color: #00000A"><strong></strong>Estradiol (E2) - 36 pg/mL 10‐40</span></p><p><span style="color: #00000A">Total T - 960.0 ng/dL 240.0 ‐ 950.0 ng/dL</span></p><p><span style="color: #00000A">Free T - 273.8 pg/mL 46.0‐224.0</span></p><p><span style="color: #00000A">TSH - 1.88 u[IU]/mL 0.35 ‐ 4.01 u[IU]/mL</span></p><p><span style="color: #00000A">SHBG - 16 nmol/L 10 - 57 nmol/L</span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"><strong>1 Week Later - Same protocol:</strong></span></p><p><span style="color: #00000A">Estradiol (E2) - 26 pg/mL 10‐40</span></p><p><span style="color: #00000A">Total T - 668 ng/dL 240.0 ‐ 950.0 ng/dL</span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A">Labs were all drawn at the same time relative to injection (on injection day and before injection). So I see my SHBG is dropping, E2 is all over the place and still very much there with a high dose of .5mg EOD Anastrazole. My total T seems to jump around as well even though I am on an EOD injection protocol. I am looking forward to joining Defy but I fear that I am a tough case. My primary concern is libido and ED, followed by energy, brain fog and general anxiety. I see so many posts about people crashing their E2 with far less of a dose than I am taking. </span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A">Any thoughts about these labs is greatly appreciated. </span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"></span></p><p><span style="color: #00000A"></span></p></blockquote><p></p>
[QUOTE="riverside, post: 58040, member: 14064"] I am 4 months in with TRT and have yet to feel/experience any benefits. Please, please look at these labs and let me know your thoughts. And let me know if you have any questions. I am moving to Defy and have my first consult with Dr. Saya in early January. My doctor now is recommending I increase my AI dose to .5mg every day and I am worried about doing so but I still have high E2 after 6 weeks of .5mg EOD. Should I increase or wait until I discuss with Defy? [B][COLOR=#00000A][FONT=Helvetica]Pre TRT:[/FONT][/COLOR][/B] [COLOR=#00000A][FONT=Helvetica]Total T = 193 ng/dL 241-827[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]Free T = 3.50 ng/dL 3.70-23.28[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]SHBG = 33.2 nmol/L 11.0-57.0[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]E2 = 2.0 μg/24hrs 0.8 – 7.0[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]FSH = 0.9 [IU]/L 1.4 - 18.1 mIU/mL[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]LH = 1.3 [IU]/L 1.5 - 8.1 mIU/mL[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]DHT = 1.6μg/24hrs 3–16[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]TSH = 1.020 uIU/mL 0.350-5.500 [B]6 Weeks of 70mg E3.5D Test-C, 200IU HCG EOD:[/B][/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]Testosterone Total - 712 ng/dL 240 - 950 ng/dL[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]Testosterone, Free - 173.9 pg/mL pg/mL[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]SHBG - 20 nmol/L 10 - 57 nmol/L[/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica]Estradiol (E2) - 63 H pg/mL 10-40[/FONT] [B]Switched to EOD injections of 40mg Test-C:[/B] [FONT=Helvetica]Estradiol (E2) - 100 H < or = 29 pg/ml[/FONT] [B]Dr added AI. After 2 weeks of .25 Anastrazole EOD: [/B][FONT=Helvetica]Estradiol (E2) - 33 H < or = 29 pg/ml[/FONT] [FONT=Helvetica]Total T - 519 250-827 ng/dL[/FONT] [B]Dr changed AI to .5mg EOD and bumped Test-C to 45mg EOD. Labs after 4 weeks: [/B][FONT=Helvetica]Estradiol (E2) - 36 pg/mL 10‐40[/FONT] [FONT=Helvetica]Total T - 960.0 ng/dL 240.0 ‐ 950.0 ng/dL[/FONT] [FONT=Helvetica]Free T - 273.8 pg/mL 46.0‐224.0[/FONT] [FONT=Helvetica]TSH - 1.88 u[IU]/mL 0.35 ‐ 4.01 u[IU]/mL[/FONT] [FONT=Helvetica]SHBG - 16 nmol/L 10 - 57 nmol/L[/FONT] [B]1 Week Later - Same protocol:[/B] [FONT=Helvetica]Estradiol (E2) - 26 pg/mL 10‐40[/FONT] [FONT=Helvetica]Total T - 668 ng/dL 240.0 ‐ 950.0 ng/dL[/FONT] [FONT=Helvetica]Labs were all drawn at the same time relative to injection (on injection day and before injection). So I see my SHBG is dropping, E2 is all over the place and still very much there with a high dose of .5mg EOD Anastrazole. My total T seems to jump around as well even though I am on an EOD injection protocol. I am looking forward to joining Defy but I fear that I am a tough case. My primary concern is libido and ED, followed by energy, brain fog and general anxiety. I see so many posts about people crashing their E2 with far less of a dose than I am taking. [/FONT] [FONT=Helvetica]Any thoughts about these labs is greatly appreciated. [/FONT][/COLOR] [COLOR=#00000A][FONT=Helvetica] [/FONT][/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
4 Months In - No Improvements - Major E2 Issues - Switching to Defy
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