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37 yr old male- former AAS user
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<blockquote data-quote="madman" data-source="post: 195603" data-attributes="member: 13851"><p>Welcome.</p><p></p><p>Keep in mind that this is a men's health/trt/hrt forum and we do not discuss testosterone/AAS use or abuse for the sole purpose of muscle enhancement whether cycling, blasting/cruising as it plays no part in maintaining long-term health!</p><p></p><p>As you would very well know there is numerous run of the mill steroid forums littered on the internet to seek out such information.</p><p></p><p>No issues with discussing your past history on here.</p><p></p><p></p><p></p><p></p><p><strong>I am here to learn about hypertension and how testosterone causes this problem for me.</strong></p><p></p><p>Many factors can come into play.</p><p></p><p>Androgens increase the retention of sodium let alone can cause water retention/bloat.</p><p></p><p>Excess water retention can drive up BP.</p><p></p><p>Androgens will increase RBCs/hematocrit/hemoglobin.</p><p></p><p>Increased hematocrit will make blood more viscous and can drive up BP.</p><p></p><p>Androgens have a tonic effect on the CNS which can interfere with sleep quality.</p><p></p><p>OSA can play a big role in driving up BP.</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/obstructive-sleep-apnea-and-trt.21725/#post-186606[/URL][ATTACH=full]12874[/ATTACH]</p><p></p><p></p><p></p><p></p><p><strong>I metabolize esters really quickly and even 280mg had me at (only) 775 ng/dl total test and 28 free test.</strong></p><p><strong></strong></p><p><strong>I want to stay at 1100ng/dl and 32 free test with all other health markers staying within range of course, otherwise numbers are arbitrary.</strong></p><p></p><p>If you are only hitting a TT 775 ng/dL on once-weekly injections of 280 mg T then these are most likely your trough (7 days post-injection) levels and you would need to keep in mind that your TT/FT/e2 levels will be much higher at true peak (8-12 hrs) post-injection and levels will be elevated during the first few days.</p><p></p><p>Even then although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>I would be much more concerned with where your trough FT level truly sits and the only way to know would be to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best).</p><p></p><p>Also, keep in mind that your SHBG level will have a significant impact on what FT level you achieve on such protocol (dose T/injection frequency).</p><p></p><p>FT 16-31 ng/dL would be considered healthy.</p><p></p><p>Most men do well with FT in the 20-30 ng/dL range.</p><p></p><p>Some may choose to run slightly higher levels but it comes down to the individual and where they feel best.</p><p></p><p>Even then keeping blood health markers in check and minimizing/avoiding any potential side-effects is critical!</p><p></p><p></p><p><strong>Not impressive, I'd like to learn more about that too. Why do I require so much?</strong></p><p></p><p>The average young healthy male produces 5-7 mg/day.</p><p></p><p>When using exogenous T many factors can come into play when it comes to what dose of T is needed to achieve a healthy FT level.</p><p></p><p>The dose T, SHBG level, injection frequency, the sensitivity of the AR, polymorphism of the AR, and CAG repeat length (long/short), bodyweight.</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/effect-of-weight-on-serum-t-with-sub-q-te-in-men-with-td.21072/[/URL]</p><p></p><p></p><p></p><p></p><p><strong><u>Nandrolone is naturally occurring in the human body (endogenous)</u> and works wonders for joint pain. It's great around 80-125mg per week on top of your Test Cyp.</strong></p><p></p><p>Sure in minuscule amounts!</p><p></p><p>Yes, it definitely can work wonders when it comes to joint/bone pain and 50-100 mg/week is the therapeutic dose used.</p><p></p><p>Testosterone is the primary sex hormone and anabolic steroid in males.</p></blockquote><p></p>
[QUOTE="madman, post: 195603, member: 13851"] Welcome. Keep in mind that this is a men's health/trt/hrt forum and we do not discuss testosterone/AAS use or abuse for the sole purpose of muscle enhancement whether cycling, blasting/cruising as it plays no part in maintaining long-term health! As you would very well know there is numerous run of the mill steroid forums littered on the internet to seek out such information. No issues with discussing your past history on here. [B]I am here to learn about hypertension and how testosterone causes this problem for me.[/B] Many factors can come into play. Androgens increase the retention of sodium let alone can cause water retention/bloat. Excess water retention can drive up BP. Androgens will increase RBCs/hematocrit/hemoglobin. Increased hematocrit will make blood more viscous and can drive up BP. Androgens have a tonic effect on the CNS which can interfere with sleep quality. OSA can play a big role in driving up BP. [URL unfurl="true"]https://www.excelmale.com/forum/threads/obstructive-sleep-apnea-and-trt.21725/#post-186606[/URL][ATTACH type="full" alt="Screenshot (3506).png"]12874[/ATTACH] [B]I metabolize esters really quickly and even 280mg had me at (only) 775 ng/dl total test and 28 free test. I want to stay at 1100ng/dl and 32 free test with all other health markers staying within range of course, otherwise numbers are arbitrary.[/B] If you are only hitting a TT 775 ng/dL on once-weekly injections of 280 mg T then these are most likely your trough (7 days post-injection) levels and you would need to keep in mind that your TT/FT/e2 levels will be much higher at true peak (8-12 hrs) post-injection and levels will be elevated during the first few days. Even then although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. I would be much more concerned with where your trough FT level truly sits and the only way to know would be to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best). Also, keep in mind that your SHBG level will have a significant impact on what FT level you achieve on such protocol (dose T/injection frequency). FT 16-31 ng/dL would be considered healthy. Most men do well with FT in the 20-30 ng/dL range. Some may choose to run slightly higher levels but it comes down to the individual and where they feel best. Even then keeping blood health markers in check and minimizing/avoiding any potential side-effects is critical! [B]Not impressive, I'd like to learn more about that too. Why do I require so much?[/B] The average young healthy male produces 5-7 mg/day. When using exogenous T many factors can come into play when it comes to what dose of T is needed to achieve a healthy FT level. The dose T, SHBG level, injection frequency, the sensitivity of the AR, polymorphism of the AR, and CAG repeat length (long/short), bodyweight. [URL unfurl="true"]https://www.excelmale.com/forum/threads/effect-of-weight-on-serum-t-with-sub-q-te-in-men-with-td.21072/[/URL] [U][/U] [B][U]Nandrolone is naturally occurring in the human body (endogenous)[/U] and works wonders for joint pain. It's great around 80-125mg per week on top of your Test Cyp.[/B] Sure in minuscule amounts! Yes, it definitely can work wonders when it comes to joint/bone pain and 50-100 mg/week is the therapeutic dose used. Testosterone is the primary sex hormone and anabolic steroid in males. [/QUOTE]
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37 yr old male- former AAS user
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