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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
33 y/o, elevated Estradiol, looking for advice
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<blockquote data-quote="zaambo" data-source="post: 141576" data-attributes="member: 30884"><p>Hi again, thanks for reminding me to post an update!</p><p></p><p>So I decided to try myself on TRT to see how I felt both mentally and physically, and see where my Estradiol levels naturally ended up, and bring in an AI if needed.</p><p></p><p>I know starting TRT is not something that my natural bloods might have pointed to as being necessary, but it's something I've been curious to see if it helped some of my long standing symptoms. I'm sure I would have had to fight with many doctors just to get a script and see, so I thought stuff it I'm sick of my T being in the lower end of the range, I'll just try it myself and see.</p><p></p><p>I started on 120mg of Test C per week, dosed every 3.5 days. Felt great! Mood improved, energy improved, all round wellness I’d say. No additional high E2 sides than what I felt in the past. I kept this protocol and got bloods 6 weeks later. Besides my test being too high (no shit I felt good!) I found my E2 and Prolactin were also sky high! :</p><table class='post-table ' style='width: 100%'><tr><td ><p>Total Testosterone</p></td><td ><p>49 nmol/L</p></td><td ><p>(8.3-29)</p></td></tr><tr><td ><p>Free Testosterone</p></td><td ><p>1425.8 pmol/L</p></td><td ><p>(225-725)</p></td></tr><tr><td ><p>Estradiol</p></td><td ><p><strong>299 pmol/L</strong></p></td><td ><p>(50-150)</p></td></tr><tr><td ><p>Prolactin</p></td><td ><p><strong>515 mIU/L</strong></p></td><td ><p>(45-375)</p></td></tr><tr><td ><p>Progesterone</p></td><td ><p>1.7 nmol/L</p></td><td ><p>(1.2-4.8)</p></td></tr><tr><td ><p>SHGB</p></td><td ><p>29 nmol/L</p></td><td ><p>(13-71)</p></td></tr></table> I decided to lower my dose to 80mg per week. Waited another 5 weeks and got tested:</p><table class='post-table ' style='width: 100%'><tr><td ><p>Total Testosterone</p></td><td ><p>24.5 nmol/L</p></td><td ><p>(8.3-29) </p></td></tr><tr><td ><p>Free Testosterone</p></td><td ><p>623 pmol/L</p></td><td ><p>(225-725)</p></td></tr><tr><td ><p>Estradiol</p></td><td ><p><strong>177 pmol/L</strong></p></td><td ><p>(50-150) </p></td></tr><tr><td ><p>Prolactin</p></td><td ><p><strong>559 mIU/L</strong></p></td><td ><p>(45-375)</p></td></tr><tr><td ><p>Progesterone</p></td><td ><p>1 nmol/L</p></td><td ><p>(1.2-4.8) </p></td></tr><tr><td ><p>SHGB</p></td><td ><p>24 nmol/L</p></td><td ><p>(13-71)</p></td></tr></table> At this point my mood had definitely reduced a somewhat, but all in all I was still a lot better off than before. One thing to note is that although my testosterone and E2 had reduced along with the dose, my Prolactin had actually increased. So apparently though, 80mg per week is too low a dose, so now as of a few weeks ago I have increased it to 100mg per week, and also started taking .25mg of Armimidex, split into two doses, on the same day I pin. Also followed the advice here for dissolving in vodka. I'll take bloods again in a few weeks to see where everything is sitting.</p><p></p><p>I'm slightly concerned about my Prolactin levels though, and unfortunately I don't have a blood level for that prior to starting TRT. From what I read though, in a worst case scenario this can be due to a benign pituitary gland tumor, that can only be assessed via an MRI. For an unrelated reason I actually need to get an MRI soon, so I am going to chat to my GP about all this, see what he thinks, and if required try and get the MRI to include a scan of my pituitary gland. </p><p></p><p>Any thoughts or suggestions you guys have about all this would be much appreciated!</p></blockquote><p></p>
[QUOTE="zaambo, post: 141576, member: 30884"] Hi again, thanks for reminding me to post an update! So I decided to try myself on TRT to see how I felt both mentally and physically, and see where my Estradiol levels naturally ended up, and bring in an AI if needed. I know starting TRT is not something that my natural bloods might have pointed to as being necessary, but it's something I've been curious to see if it helped some of my long standing symptoms. I'm sure I would have had to fight with many doctors just to get a script and see, so I thought stuff it I'm sick of my T being in the lower end of the range, I'll just try it myself and see. I started on 120mg of Test C per week, dosed every 3.5 days. Felt great! Mood improved, energy improved, all round wellness I’d say. No additional high E2 sides than what I felt in the past. I kept this protocol and got bloods 6 weeks later. Besides my test being too high (no shit I felt good!) I found my E2 and Prolactin were also sky high! : [TABLE][TR][TD] Total Testosterone [/TD] [TD] 49 nmol/L [/TD] [TD] (8.3-29) [/TD][/TR] [TR][TD] Free Testosterone [/TD] [TD] 1425.8 pmol/L [/TD] [TD] (225-725) [/TD][/TR] [TR][TD] Estradiol [/TD] [TD] [B]299 pmol/L[/B] [/TD][TD] (50-150) [/TD][/TR] [TR][TD] Prolactin [/TD] [TD] [B]515 mIU/L[/B] [/TD][TD] (45-375) [/TD][/TR] [TR][TD] Progesterone [/TD] [TD] 1.7 nmol/L [/TD][TD] (1.2-4.8) [/TD][/TR] [TR][TD] SHGB [/TD] [TD] 29 nmol/L [/TD][TD] (13-71) [/TD][/TR][/TABLE] I decided to lower my dose to 80mg per week. Waited another 5 weeks and got tested: [TABLE][TR][TD] Total Testosterone [/TD] [TD] 24.5 nmol/L [/TD] [TD] (8.3-29) [/TD][/TR] [TR][TD] Free Testosterone [/TD][TD] 623 pmol/L [/TD] [TD] (225-725) [/TD][/TR] [TR][TD] Estradiol [/TD] [TD] [B]177 pmol/L[/B] [/TD] [TD] (50-150) [/TD][/TR] [TR][TD] Prolactin [/TD] [TD] [B]559 mIU/L[/B] [/TD] [TD] (45-375) [/TD][/TR] [TR][TD] Progesterone [/TD] [TD] 1 nmol/L [/TD] [TD] (1.2-4.8) [/TD][/TR] [TR][TD] SHGB [/TD] [TD] 24 nmol/L [/TD] [TD] (13-71) [/TD][/TR][/TABLE] At this point my mood had definitely reduced a somewhat, but all in all I was still a lot better off than before. One thing to note is that although my testosterone and E2 had reduced along with the dose, my Prolactin had actually increased. So apparently though, 80mg per week is too low a dose, so now as of a few weeks ago I have increased it to 100mg per week, and also started taking .25mg of Armimidex, split into two doses, on the same day I pin. Also followed the advice here for dissolving in vodka. I'll take bloods again in a few weeks to see where everything is sitting. I'm slightly concerned about my Prolactin levels though, and unfortunately I don't have a blood level for that prior to starting TRT. From what I read though, in a worst case scenario this can be due to a benign pituitary gland tumor, that can only be assessed via an MRI. For an unrelated reason I actually need to get an MRI soon, so I am going to chat to my GP about all this, see what he thinks, and if required try and get the MRI to include a scan of my pituitary gland. Any thoughts or suggestions you guys have about all this would be much appreciated! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
33 y/o, elevated Estradiol, looking for advice
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