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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
31yo. Pre-TRT bloods. Low free test, low LH, high prolactin, albumin, SHBG
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<blockquote data-quote="madman" data-source="post: 209537" data-attributes="member: 13851"><p>Unfortunately, you had your FT tested using the piss poor direct immunoassay which is known to be inaccurate.</p><p></p><p>The only way to know where your FT truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best).</p><p></p><p>Sure you can also use the older outdated calculated methods but I would not rely upon such especially in cases of altered SHBG.</p><p></p><p>Although your TT 460 ng/dL would seem far from low your SHBG is highish 40.6 nmol/L and Albumin slightly elevated 5.2 g/dL so your FT would most likely be low and definitely suboptimal!</p><p></p><p>Too many doctors let alone men looking into starting trt get caught up on TT and although it is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>Even then many of the doctors let alone men on trt are using/relying upon inaccurate assays when testing FT.</p><p></p><p>Critical to use accurate assays when testing.</p><p></p><p>Excess (very high) levels of prolactin can have a negative impact on libido.</p><p></p><p>Prolactin <425 µg/L (20 ng/mL) in most cases would not be a cause for concern.</p><p></p><p>Comes down to the individual and although yours is slightly elevated it is far from being considered absurdly high.</p></blockquote><p></p>
[QUOTE="madman, post: 209537, member: 13851"] Unfortunately, you had your FT tested using the piss poor direct immunoassay which is known to be inaccurate. The only way to know where your FT truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best). Sure you can also use the older outdated calculated methods but I would not rely upon such especially in cases of altered SHBG. Although your TT 460 ng/dL would seem far from low your SHBG is highish 40.6 nmol/L and Albumin slightly elevated 5.2 g/dL so your FT would most likely be low and definitely suboptimal! Too many doctors let alone men looking into starting trt get caught up on TT and although it is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. Even then many of the doctors let alone men on trt are using/relying upon inaccurate assays when testing FT. Critical to use accurate assays when testing. Excess (very high) levels of prolactin can have a negative impact on libido. Prolactin <425 µg/L (20 ng/mL) in most cases would not be a cause for concern. Comes down to the individual and although yours is slightly elevated it is far from being considered absurdly high. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
31yo. Pre-TRT bloods. Low free test, low LH, high prolactin, albumin, SHBG
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