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I normally do not post to forums as a physician for a variety of legal and ethical reasons , but this site is insightful and supportive and I think has excellent members with a great deal of anecdotal information that should be utilized by docs . Depending on the patient’s issues and depending on the their sensitivity to specific receptors sites as well as Hormonal feedback mechanisms , adrenal/ thyroid function , comorbid illness, overall pituitary function / defect , medications used / doses,  sleep architecture, TRT can be extremely difficult to stop abruptly at even at low doses. Tapering  doses over time can slowly bring a a person to a steady state except for when TRT has affected other tissues/ organs  that may have developed  hypo/ hyperplasia changes  in tissue structure and function. So even if a patient can get back to pre TRT levels , hormone use may have caused growth or shrinkage of other tissue as a secondary affect which now function differently and can affect the person as a whole no matter what pre TRT hormonal levels were- very complicated for all of us .


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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