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Low E2 can cause excessive urination, as well as excessive thirst.


When my E2 was low, I had to urinate every hour almost, and it'd feel like an emergency every time. The thirst was probably the worst part, I would wake up so damned thirsty every morning, drink about 32oz of water, run to the bathroom and still be thirsty. There was no satisfying it.


I don't know much about anal fissures, but did clomid help the urination issue? Did you have any labs taken while on it?


TRT is not a bad option for levels like yours, although you'll need a few more labs prior to starting it.


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