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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
29 Medications That May Cause Adverse Interactions with Thyroid Drugs
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<blockquote data-quote="Vettester Chris" data-source="post: 15350" data-attributes="member: 696"><p>I have experience with both medications. You "could" see some better results with going NDT, as many know I'm a proponent of it. However, implementing NDT now also implements T4 into the mix, so there are other variables in play. One main one will be ensuring that T4 is converting adequately to T3, and not excessively converting to Reverse T3. I would make sure your cortisol is where it needs to be, and make sure iodine and selenium is supplemented if needed. </p><p></p><p>As far as doing the actual switch ... If it were me, the first week, I would drop 10mcg of the T3 each day and add 1 grain of NDT. Keep in mind, one (1) grain of NDT right off the bat will have approx. 9 to 10mcg of T3. You will want the first week of NDT to get T4 built up a bit and converting down to T3. See where you're at and how you feel after the first week. The one grain (60mcg) of NDT will play out to equal approx. 25mcg of Cytomel (give or take a few mcgs). At that point you should be able to transition off the T3 Cytomel completely.</p><p></p><p>You will not only want to base this with how you feel, but you will want to run labs after about a month. You will want to see FT4, FT3, Reverse T3, and throw a TSH in as well. If you haven't run antibodies, then run them (TPO & TgAb). IF they have been checked, no worries. We will want to see how the close the FT4 & FT3 labs are together in their respective reference ranges, and compare the ratio with FT3 & RT3. To reiterate, depending on how you're feeling, this is where you might want to titrate your dosage up (can't imagine it going down), and/or possible addition of a little T4 is added, since the ratio of T4 to T3 is different with NDT's than what the actual human thyroid would produce naturally. </p><p></p><p>It's a gradual process of titration to get to where you feel just right, and your lab values are where you want them. I'd suggest stepping up a 1/2 grain when doing this."Most" cases, you might want to be shooting for 50% to 80% of the reference range value with both FT4 and FT3, and aiming to keep Reverse T3 at a respectable ratio compared to FT3; usually > 20. </p><p></p><p>If you don't feel better, or even start feeling worse, RT3 could very well be the culprit. Labs will tell you what's going on, and they will also be a marker to look at other areas like cortisol, iron & ferritin, B12, D3 & electrolytes "if" you are experiencing issues, or inconsistent patterns with your well being related to your treatment program.</p></blockquote><p></p>
[QUOTE="Vettester Chris, post: 15350, member: 696"] I have experience with both medications. You "could" see some better results with going NDT, as many know I'm a proponent of it. However, implementing NDT now also implements T4 into the mix, so there are other variables in play. One main one will be ensuring that T4 is converting adequately to T3, and not excessively converting to Reverse T3. I would make sure your cortisol is where it needs to be, and make sure iodine and selenium is supplemented if needed. As far as doing the actual switch ... If it were me, the first week, I would drop 10mcg of the T3 each day and add 1 grain of NDT. Keep in mind, one (1) grain of NDT right off the bat will have approx. 9 to 10mcg of T3. You will want the first week of NDT to get T4 built up a bit and converting down to T3. See where you're at and how you feel after the first week. The one grain (60mcg) of NDT will play out to equal approx. 25mcg of Cytomel (give or take a few mcgs). At that point you should be able to transition off the T3 Cytomel completely. You will not only want to base this with how you feel, but you will want to run labs after about a month. You will want to see FT4, FT3, Reverse T3, and throw a TSH in as well. If you haven't run antibodies, then run them (TPO & TgAb). IF they have been checked, no worries. We will want to see how the close the FT4 & FT3 labs are together in their respective reference ranges, and compare the ratio with FT3 & RT3. To reiterate, depending on how you're feeling, this is where you might want to titrate your dosage up (can't imagine it going down), and/or possible addition of a little T4 is added, since the ratio of T4 to T3 is different with NDT's than what the actual human thyroid would produce naturally. It's a gradual process of titration to get to where you feel just right, and your lab values are where you want them. I'd suggest stepping up a 1/2 grain when doing this."Most" cases, you might want to be shooting for 50% to 80% of the reference range value with both FT4 and FT3, and aiming to keep Reverse T3 at a respectable ratio compared to FT3; usually > 20. If you don't feel better, or even start feeling worse, RT3 could very well be the culprit. Labs will tell you what's going on, and they will also be a marker to look at other areas like cortisol, iron & ferritin, B12, D3 & electrolytes "if" you are experiencing issues, or inconsistent patterns with your well being related to your treatment program. [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
29 Medications That May Cause Adverse Interactions with Thyroid Drugs
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