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Thanks for posting. I thought the study sounded familiar, and indeed we did mention it here. It is interesting that when delivered in the right manner an otherwise suppressive drug can continue to stimulate the HPTA. I think two important factors here are the low dose and the relatively short half-life of buserelin compared to other synthetic GnRH analogs. These results may be harder to reproduce with triptorelin, which appears to have a half-life that is 2-3 times longer.