1st Lab Results (Pre-Consultation)

FastCat

New Member
43yo, 5-10 180, athletic-type build. Fatigue issues have been mounting for the last few years. Energy levels down. Moody with a tendency to dwell on negatives for a few days. For many years, I was robotic in hitting the weights, exercising and eating right to the point where I put up some really nice numbers in the weight room. For about two years, I have not been able to sustain any weight training for longer than 4-5 weeks before feeling awful....even when just focusing on light weights. Anyways, had labs ran and then consulted with Defy.

Labs:
TT: 668 (264-916)
FT: 9.2 (6.8-21.5)
LH: 4.7 (1.7-8.6)
DHEAS: 181 (102-416)
E2: 23 (8-35)
SHBG: 68 (16-56)

Protocol Recommendation:
TestC: 80mg/2x wk (Mon & Thur)
HCG: 500IU/ 2x wk
AI: .125/2x wk

DHEA: 50mg/day
D3: 5000IU/day
CoQ10: 100/day
Fish Oil
 
Ever have your thyroid checked? What are your body temperatures in the morning and mid afternoon?

TRT and raising DHEA should lower that SHBG. As far as testosterone is concerned, TT is solid for your age but that high SHBG is lowering FT.
 
First reaction; something else in play causing your problems, many possibilities; Thyroid, adrenal, infection, drug side effect, anemia, sleep apnea, autoimmune, overtraining/not resting enough, etc

I'd just about kill for those T, Free T, E2 and DHEA numbers! I personally would have never started TRT. YMMV.
 
I'd go along with these two, TRT is a little suspect with those numbers though I know we can talk about symptom based treatment and treatment of the low FT/high SHBG. I might have been more wary to TRT with those numbers myself.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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