How ironic is this! Lol. After all this diabetes talk, turns out you’re a diabetes rep?? That’s it, I’m convinced we’re in a simulation now haha. But yes, Dhea can definitely raise E2, but that’s usually only if you take doses that are on the higher end of the scale. Here’s a good video explaining that studies have shown, as well as anecdotal accounts, that men may get the same benefit from DHEA with much much smaller doses, without the side effect of E2 increasing too much.
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I believe the studies say that as long as you stay under 15mg per day, that you will avoid most of the side effects. A doctor with a famous forum Ray Peat, for example, takes 5mgs per day, with good results apparently. Even if you end up needing a much higher dose, just start very slow and titrate up if needed. With DHEA, there’s no feedback loop. So it won’t shut off your endogenous production, it only adds to whatever natural production you have going on. So no reason to start with 25mg or anything. I would personally start with 5mg, and titrate up if needed.