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10 Year Zero Carb Carnivore Veteran Loses Weight and Shares Healing Story
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<blockquote data-quote="Guided_by_Voices" data-source="post: 167057" data-attributes="member: 15235"><p>What studies? None. Studies, especially observational ones, are of such low quality to be usually worse than worthless. I use, logic, evidence, and risk/reward.</p><p></p><p>When people think of higher BMI they usually mean higher body fat, so if that was driving longer (and presumably healthier) life, there should be a known mechanism, however almost all the mechanisms I am aware of are negative. Fat, especially visceral fat, apparently increases inflammatory signaling, and since excess inflammation seems to be one of the ways the body tries to kill itself as part of aging, we certainly want to err on the side of low inflammation.</p><p></p><p>Even if you had some relatively benign adipose fat, it becomes harder to see if you're adding visceral fat if there is adipose fat covering it up. This is one of many arguments against so-called metabolically healthy obesity. And 10-15 pounds of extra fat of any kind is going to multiply the force on the knee/hip/ankle joints when doing youthful activities such as basketball or even tennis. Not good.</p><p></p><p>A bit of fat is likely a good defense against a serious illness that precludes eating a lot, however fat is so energy-dense that I doubt you need enough to significantly raise BMI to have that benefit.</p><p></p><p>Extra muscle is desirable for a number of reasons (e.g. myokines, maintaining healthy activity levels, injury prevention and recovery) and would raise BMI, but that does not argue against leanness except to the degree that it's easier to add muscle if a small amount of fat is added as well, presumably as a signal that the body is in a state of abundance.</p><p></p><p>From a practical standpoint, there is more evidence all the time that true multi-day fasting from time to time has many longevity and health benefits, and to maintain much extra bodyfat may be difficult for everyone but endomorphs if fasting is part of one's eating pattern.</p><p></p><p>While I think the benefits of so-called calorie restriction are overstated and also partially based on dubious "science", there is also likely something to it, so if someone is proposing that chronic overfeeding is somehow a good thing, then the conflict with CR would need to be reconciled. I'm not aware of anything that does this other than noting as I did above that extreme leanness likely puts one at risk for death from infection.</p><p></p><p>Higher BMI could be correlated with lots of other good things such as better nutrient status, however the action there is to improve your nutrient status, not raise body fat.</p><p></p><p>Even if endomorphs have some longevity benefit (perhaps that body type is correlated with some other benefit) that does not mean that ectomorphs would benefit from adding fat, especially since they, in my observation, seem to be especially prone to visceral fat. Yet another reason that correlation studies are almost never actionable.</p><p></p><p>So the bottom line is that the best evidence suggests that if you want to raise your BMI by adding muscle (while also pursing intermittent down-regulation of growth mechanisms like mTOR such as by fasting and rapamycin) then go for it, it is almost certainly a benefit. But trying to add a significant amount of extra fat is most likely going to shorten your life and more importantly, distract you from doing other things that might have actually helped, even if it raises your BMI to correlate with supposedly greater longevity.</p></blockquote><p></p>
[QUOTE="Guided_by_Voices, post: 167057, member: 15235"] What studies? None. Studies, especially observational ones, are of such low quality to be usually worse than worthless. I use, logic, evidence, and risk/reward. When people think of higher BMI they usually mean higher body fat, so if that was driving longer (and presumably healthier) life, there should be a known mechanism, however almost all the mechanisms I am aware of are negative. Fat, especially visceral fat, apparently increases inflammatory signaling, and since excess inflammation seems to be one of the ways the body tries to kill itself as part of aging, we certainly want to err on the side of low inflammation. Even if you had some relatively benign adipose fat, it becomes harder to see if you're adding visceral fat if there is adipose fat covering it up. This is one of many arguments against so-called metabolically healthy obesity. And 10-15 pounds of extra fat of any kind is going to multiply the force on the knee/hip/ankle joints when doing youthful activities such as basketball or even tennis. Not good. A bit of fat is likely a good defense against a serious illness that precludes eating a lot, however fat is so energy-dense that I doubt you need enough to significantly raise BMI to have that benefit. Extra muscle is desirable for a number of reasons (e.g. myokines, maintaining healthy activity levels, injury prevention and recovery) and would raise BMI, but that does not argue against leanness except to the degree that it's easier to add muscle if a small amount of fat is added as well, presumably as a signal that the body is in a state of abundance. From a practical standpoint, there is more evidence all the time that true multi-day fasting from time to time has many longevity and health benefits, and to maintain much extra bodyfat may be difficult for everyone but endomorphs if fasting is part of one's eating pattern. While I think the benefits of so-called calorie restriction are overstated and also partially based on dubious "science", there is also likely something to it, so if someone is proposing that chronic overfeeding is somehow a good thing, then the conflict with CR would need to be reconciled. I'm not aware of anything that does this other than noting as I did above that extreme leanness likely puts one at risk for death from infection. Higher BMI could be correlated with lots of other good things such as better nutrient status, however the action there is to improve your nutrient status, not raise body fat. Even if endomorphs have some longevity benefit (perhaps that body type is correlated with some other benefit) that does not mean that ectomorphs would benefit from adding fat, especially since they, in my observation, seem to be especially prone to visceral fat. Yet another reason that correlation studies are almost never actionable. So the bottom line is that the best evidence suggests that if you want to raise your BMI by adding muscle (while also pursing intermittent down-regulation of growth mechanisms like mTOR such as by fasting and rapamycin) then go for it, it is almost certainly a benefit. But trying to add a significant amount of extra fat is most likely going to shorten your life and more importantly, distract you from doing other things that might have actually helped, even if it raises your BMI to correlate with supposedly greater longevity. [/QUOTE]
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10 Year Zero Carb Carnivore Veteran Loses Weight and Shares Healing Story
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