Topical Retinoids

* Four main interrelated pathogenic factors, that act synergistically in a complex manner are involved in the development of acne lesions: 1. Increased sebum production due to androgen-driven sebaceous gland hyperplasia; 2. Hyperkeratinization of the follicular epithelium due to abnormal...

Management of Acne Vulgaris With Trifarotene (2023) Jerry Tan, MD, Rajeev Chavda, MD, Hilary Baldwin, MD, and Brigitte Dreno, MD, PhD Abstract Topical retinoids have an essential role in the treatment of acne. Trifarotene, a topical retinoid selective for retinoic acid receptor (RAR) γ, is...

Abstract Acne vulgaris is a common skin condition of the face and trunk that negatively impacts the quality of life. Trifarotene is a new first-in-class fourth-generation topical retinoid that has been uniquely studied in the treatment of both facial and truncal acne. Through selective agonism...