t/e2 ratio

  1. Nelson Vergel

    Managing the Testosterone-to-Estradiol Ratio in Men on TRT

    Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the testosterone-to-estradiol (T:E) ratio, a metric...
  2. Nelson Vergel

    A Review on Testosterone: Estradiol Ratio—Does It Matter, How Do You Measure It, and Can You Optimize It?

    There is a natural balance between the major sex steroids, testosterone and estradiol, controlled by gonadal secretion and peripheral conversion by aromatase. This balance is impacted by a variety of inborn and acquired conditions, and, more recently, by a growing use of exogenous testosterone...
  3. Jaydubbs

    E2 Excessively High?

    I'm 70yo, and have been on Test Cyp for about 14 months. Started at 180mg split in two injections, and lowered that to 140mg split in two injections weekly in January. I stumbled across a T/E2 calculator that had my e2 ratio at 180??? Last test in September: Total 1251 (blood drawn at the low...
  4. M

    E2 too low, what to do?

    Been having problems with too little aromatization a while, started while i was on hcg, maybe it was jacking up progesterone and suppressing e2. Kind of ironic since usually hcg leads to higher e2. Anyway, been trying ed enanthate now, at 7.5mg, felt good for a while but once i was reaching...
  5. Nelson Vergel

    Nelson Vergel Talks About Nandrolone, hCG, Hormone Ratios, AI’s, and More

  6. 3

    E2 to T Ratio: When is higher E2 better?

    My Total T (trough) is around 1,300. My E2 is at 26. That's a low E2 ratio...too low? I've always read/heard that mid 20's is best, but at what T level? According to the E2:T ratio calculation I found [min is (Total T)/20, max is (Total T)/14)] I should be between 65 and 93. But would that...
  7. Nelson Vergel

    Testosterone to estradiol ratio reflects inflammation and predicts future cardiovascular events in men

    Testosterone to oestradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular events in men with severe atherosclerosis Cardiovascular Research, cvy188, Testosterone to oestradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular...
  8. R

    t/e2 ratio off optimal ratio

    Hello guys, been suffering with symptoms of low t even though the last test I had last year I was "in range". I have been doing research trying to figure out what could be wrong, I had originally thought I had high e2 but was in range. But while doing my research I can across these 2 threads...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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