Reproduction

* We demonstrate the clinical potential for intranasal kisspeptin delivery as the first non-invasive method to robustly and safely stimulate gonadotropins with kisspeptin and potentially transform the management of reproductive disorders. * In summary, we provide the first human evidence...

https://www.endocrine-abstracts.org/ea/0094/ea0094oc4.4 Background Kisspeptin is a potent regulator of GnRH neurons with the potential to treat reproductive and psychosexual disorders. However, administration is limited to the subcutaneous or intravenous routes. These invasive routes limit...

Kisspeptin (KP) and neurokinin B (NKB) regulate the reproductive endocrine axis by influencing GnRH activity and secretion. Inactivating variants in KP or NKB signaling can lead to hypogonadotropic hypogonadism and pubertal development failure. KP and NKB offer potential therapeutic applications...

What is kisspeptin and why are men using it? ExcelMale's guide covers how kisspeptin works, reported benefits for testosterone and libido, and dosing protocols. Novel therapeutic avenues for kisspeptin (2022) Jovanna Tsoutsoukia, Ali Abbarab, and Waljit Dhillo Abstract Kisspeptin is a...