Reference Ranges

  1. madman

    Mapping of sex hormones in the testicular vein of healthy men

    * Our detailed quantification of hormones in the testicular vein of healthy men provides unprecedented insight into the endocrine function of the testis under physiological conditions. Although some measurements align with previous findings from varicocele, hernia, and infertile patients, others...
  2. madman

    A More Appropriate Ferritin Threshold is Cost-Effective for Iron Deficiency Screening

    * The current world health organization guidelines have the lower limit of normal for serum ferritin at 15 micrograms per liter, whereas we know from physiological studies… that a more appropriate threshold is probably 25-to-30, maybe even as high as 50 micrograms per liter Iron...
  3. madman

    Harmonization of Immunoassay Reference Intervals with LC-MS/MS for Total and Calculated Free Testosterone Measurement

    * harmonized reference ranges for total and calculated free testosterone in adults using the Siemens Atellica immunoassay, validated against a reference method. * Reference intervals were adopted from the reference laboratory and verified using 20 male and 20 female healthy samples. *...
  4. T

    Better with high free T or total T or both?

    Hi all. Was wondering which is more "important". Free testosterone or total. I had my annual bloodwork done required by my provider in November of last year. Total testosterone was 1100 ng/dl. Free test was 20.8 pg/mL. E2 was 34 pg/mL. SHBG was 36 nmol/L. I was injecting IM. I switched...
  5. madman

    CDC’s Clinical Standardization Programs

    High-quality disease biomarker tests are critical for the correct diagnosis and treatment of patients, accurate interpretation of research data, and effective use of research findings in health care. CDC’s Clinical Standardization Program (CDC CSP) assists researchers and laboratories with...
  6. madman

    Direct Measurements of Free Hormones Using Mass Spectrometry-Based Methods

    Only at Excel, are we gonna take you deep! Clinical Utility and Analytical Aspects of Direct Measurements of Free Hormones Using Mass Spectrometry-Based Methods (2022) Mark M. Kushnir, Heather A. Nelson, and Kelly Doyle Background The free hormone (FH) hypothesis states that hormone...
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