Objective To investigate the incidence of new onset type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors (dutasteride or finasteride) for long term treatment of benign prostatic hyperplasia.
Design Population based cohort study.
Setting UK Clinical Practice Research Datalink...
Seven hundred men participated in the study. Of those, 470 (mean age 58) took 5 mg of finasteride each day. The remaining 230 men (mean age 63) took 0.4 mg of tamsulosin. The men were followed for up to 45 months.
Every three months, and at follow-up appointments, the men's testosterone levels...
This super elegantly done study looked at the effect of testosterone and DHT on body fat and insulin sensitivity. The researchers previously did a similar study that determined that low estradiol was linked to increased fat mass. By blocking testosterone, DHT and estradiol in different arms...
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