premature evacuation; kh-001; sert inhibitor

First-of-Its-Kind PE Pill Unveiled at 2025 Sexual Medicine Meeting—A Major Win for Men’s Health

On demand rapid ON/OFF! * The company’s candidate, KH-001, is derived from a plant long used in traditional South African medicine. The active alkaloid targets the serotonin transporter, acting through the same molecular pathway as selective serotonin reuptake inhibitors (SSRIs) but with...
- madman
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- Saturday at 11:33 AM
- premature evacuation; kh-001; sert inhibitor
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New Breakthrough in Premature Ejaculation Treatment: KH-001 From the Kanna Plant Shows Promise

* KH-001 is an alkaloid derived from the South African Kanna plant and functions as a selective, high-potency serotonin reuptake transporter (SERT) inhibitor and phosphodiesterase inhibitor. * The starting dose of 0.5 mg was selected based on anticipated sub-therapeutic levels. Dose...
- madman
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- Aug 21, 2025
- premature evacuation; kh-001; sert inhibitor
- Replies: 2
- Forum: Health & Wellness

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038