pde 5 inhibitors

  1. S

    Frequent viagra use correlates with a reduced risk of heart attack in men with cardiovascular disease

    https://www.healthline.com/health-news/viagra-may-help-men-with-coronary-artery-disease-live-longer
  2. D

    Nitric oxide vs antioxidants

    Hey guys, I like to use arginine, citrulline, etc to encourage nitric oxide for blood flow as do some others. However it's come to my attention that at some point it's a free radical. Also using antioxidants may decrease nitric oxide? How do we get the best of both worlds? Any thoughts?
  3. D

    Cooper Pharma purity

    Hi all, First off I want to say that I have loved this forum, Nelson and the mods have been very friendly and helpful with my questions so far. In this post I am inquiring about Alldaychemist and the purity of their products. I have seen studies online stating that tadalafil laced with diabetes...
  4. J

    How does high estrogen cause poor erections and low libido?

    Are there any scientific/medical explanations as to how and why high estrogen will cause weak erections or "up and down" erections and/or a poor libido? Also of note, why can PDE5 medications ( Cialis, Viagra ) mask or override high e2 and allow for a decent erection? Does high e2 do something...
  5. Nelson Vergel

    Erectile Dysfunction and Phosphodiesterase Type 5 Inhibitor Use

    "Although the majority of PDE5i users in ELSA reported the effect of these medications on their sex lives as positive, when compared with men without ED they consistently reported higher levels of concern and dissatisfaction with various aspects of their sexual activity, function and...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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