lowering e2

B
Lost some weight. Free, Total, E2 are now high. Options?

I've been on a fairly standard Defy protocol that hasn't changed much in 2.5 years. M-W-F injections 50 cypionate, 300 HCG, 50 mg DHEA, .25 Arimidex (not now). As I've lost weight, my levels have all shot up. 01-2017 242 lbs 283 Total Start TRT 08-2017 (240 lbs) Total - 646 Free - 22.22...
- BradWI
- Thread
- Sep 2, 2019
- hcg + trt lowering e2 stopping trt
- Replies: 3
- Forum: Testosterone Basics & Questions
S
How quickly does E2 drop after lowering test dose?

I've been on trt through Defy for nine weeks now and had to drop my test dose from 160mg/wk split into two doses to 120/wk two doses because of E2 sides. Defy also sent me some compounded anastrozole in .25mg doses to take twice per week for a total of 0.5mg/wk. I really do not want to have the...
- selous
- Thread
- Sep 29, 2016
- Replies: 29
- Forum: Testosterone Side Effect Management

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038