klinefelter's syndrome

  1. D

    Etiology: What do you think caused your low T (hypogonadism)?

    Hey everyone, I had a though and felt I'd ask everyone. What do you think caused your hypogonadism? I was thinking about my etiology and realized I don't particularly have one. I did have an one sided orchiectomy (removal of testicle) for cryptorchidism, but that wouldn't have an effect on my...
  2. C

    Klinefelter's Syndrome help with TRT

    So I have KS and i find that most of the information here doesn't help me because I have primary hypogonadism, but there is no resources online for correct dosing and protocols for TRT for people with Klinefelter's. So, I want to start one here. Currently, I am on 1mg Anastrozole a week and...
  3. C

    DVT-PE in Klinefelter's syndrome

    Men with Klinefelter's syndrome usually start testosterone replacement therapy (TRT) in early adolescence and take it life long. Likelihood of DVT-PE in Klinefelter's is 20 times that of the normal population, or about 1 in 50 men. We have new data that most men with Klinefelter's who develop...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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