kisspeptin-54;anxiety; cortisol; psychosexual

"Intranasal Kisspeptin-54 Unveils Rapid Olfactory-Reproductive Pathway in Humans"

https://www.endocrine-abstracts.org/ea/0109/ea0109oc3.6 Background The most well-described pathway for kisspeptin’s activation of the reproductive axis relies on activation of kisspeptin receptors on GnRH-neurons in the hypothalamus. However, recent evidence has identified an...
- madman
- Thread
- Mar 8, 2025
- kisspeptin-54;anxiety; cortisol; psychosexual
- Replies: 1
- Forum: Testosterone and Men's Health Articles
Kisspeptin-54 administration does not alter anxiety or circulating cortisol levels in humans

https://www.endocrine-abstracts.org/ea/0099/ea0099oc9.4 Background The neuropeptide kisspeptin is a key endogenous activator of the reproductive system. Due to its crucial role in modulating reproductive and behavioural processes, there has been accelerating interest in targeting...
- madman
- Thread
- May 12, 2024
- kisspeptin-54;anxiety; cortisol; psychosexual
- Replies: 3
- Forum: Mental Health

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038