interactions

  1. A

    Testosterone cypionate drug interaction

    I am on testosterone cypionate weekly injections and was prescribed Bactrim DS for my acne by me derma. Bactrim blocks many of the cyp enzymes that break down certain drugs and I was wondering if this would interfere at all with testosterone cypionate metabolism?
  2. R

    Seroquel / Dopaquel and T, SHBG levels

    Anyone know if Seroquel/Dopaquel (Quetiapine) affects total, free T and SHBG levels? I take half a 25mg pill as off label use for sleep about 3 times a week as needed. It works really well, but my SHBG level is 63 nmol/L and wondered if it spiked due to the Seroquel.
  3. Nelson Vergel

    Avoiding Drug-Food Interactions

    What you eat and drink can affect the way your medicines work. Use this guide to alert you to possible “food-drug interactions” and to help you learn what you can do to prevent them. In this guide, a food-drug interaction is a change in how a medicine works caused by food, caffeine, or...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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