Very recent paper from October 2022.
I'm not one to push for constant higher Free T levels or the idea that everyone 70 years ago was walking around with 1700ng/dL TT levels, but I thought this was interesting. They used equilibrium dialysis and a nonobese ("healthy") population of men, coming...
Abstract
The present study was designed to assess the responsiveness of the hypothalamic-pituitary-gonadal axis to kisspeptin administration with increasing age in men. Human kisspeptin‐10 was administered in a single iv bolus dose (1 µg/kg BW) to healthy adult, middle and advanced-age men...
Predict estradiol, DHT, and free testosterone levels based on total testosterone
⚠️ Medical Disclaimer
This tool provides predictions based on statistical models and should NOT replace professional medical advice.
Always consult with your healthcare provider before making any changes to your TRT protocol.
ℹ️ Input Parameters
Normal range: 300-1000 ng/dL
Predicted Hormone Levels
Enter your total testosterone value to see predictions
Results will appear here after calculation
Understanding Your Hormones
Estradiol (E2)
A form of estrogen produced from testosterone. Important for bone health, mood, and libido.
Too high can cause side effects; too low can affect well-being.
DHT
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth,
prostate health, and masculinization effects.
Free Testosterone
The biologically active form of testosterone not bound to proteins.
Directly available for cellular uptake and biological effects.
Scientific Reference
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
