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    Metformin Weight Loss Combo: Effect of Leucine plus Metformin and Sildenafil Combination

    Objective: Leucine was previously demonstrated to allosterically activate mammalian sirtuin 1 and synergize with other sirtuin 1/AMP-activated protein kinase/nitric oxide pathway activators to modulate energy metabolism. The objective of this study was to evaluate the effects of a triple...
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