hypogonadism; testosterone; lh/hpta; fertility

Testosterone and LH Levels Are Falling in Healthy Men: New Evidence of a Global Reset in Male Hormone Health

Meta-regression analysis, using testosterone serum levels as effect of the regression, the years of sample collection as covariates and subjects’ number, age and BMI as co-factors (BMI was available for 742 study groups). Statistical details are reported in Supplementary material PODCAST...
- madman
- Thread
- Aug 2, 2025
- hypogonadism; testosterone; lh/hpta; fertility
- Replies: 6
- Forum: Testosterone and Men's Health Articles

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038