hypogonadism; opioids; testosterone; ed; screening

Opioid-induced androgen deficiency in men: Prevalence, pathophysiology, and efficacy of testosterone therapy

FIGURE 1 Direct and indirect mechanisms by which opioids cause hypogonadism. +, stimulation; -, inhibition; FSH, follicle-stimulating hormone; GnRH, gonadotropin-releasing hormone; LH, luteinizing hormone; PRL, prolactin; T, testosterone. Abstract Background Opioid analgesics are...
- madman
- Thread
- Feb 22, 2025
- hypogonadism; opioids; testosterone; ed; screening
- Replies: 7
- Forum: Health & Wellness
Assessing men with opioid use disorder for T deficiency after the development of symptoms

ABSTRACT Objective Individuals with opioid use disorder (OUD) have reduced life expectancy and inferior outcomes when treated for depression, diabetes, and fractures. Their elevated risk of testosterone deficiency may contribute to all of these relationships, however few individuals prescribed...
- madman
- Thread
- Apr 26, 2024
- hypogonadism; opioids; testosterone; ed; screening
- Replies: 4
- Forum: Testosterone and Men's Health Articles

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038