hypogonadism; free testosterone; ed assay

* In cases where binding protein concentrations are altered, total testosterone is an unreliable measure of androgen status. Measuring FT can help evaluate androgen status in women and hypogonadal men with normal or borderline total testosterone and/or cases with altered binding proteins...

* Equilibrium dialysis (ED) is the preferred method for measuring FT, followed by ultrafiltration, but these methods are technically challenging and time-consuming. Calculation of FT from total testosterone and SHBG (with or without albumin) has limitations and may be inaccurate. There is a...