hrt; estradiol ;postmenopausal; vaginal atrophy

Current and emerging estrogen receptor agonists for vaginal atrophy

ABSTRACT Introduction Vulvovaginal atrophy (VVA) predominantly affects postmenopausal women due to hormonal decline but can also occur in premenopausal women with conditions such as primary ovarian insufficiency or exposure to anti-estrogen medications. Contributing factors include smoking and...
- madman
- Thread
- Jan 25, 2025
- hrt; estradiol ;postmenopausal; vaginal atrophy
- Replies: 4
- Forum: HRT in Women
Efficacy and Safety of Intravaginal Estrogen in the Treatment of Atrophic Vaginitis

Objectives Postmenopausal females often experience genitourinary symptoms like vulvovaginal dryness due to estrogen decline. Hormone replacement therapy is effective in alleviating vaginal atrophy and genitourinary syndrome in this population. Evaluate local estrogen’s safety and effectiveness...
- madman
- Thread
- Sep 27, 2024
- hrt; estradiol ;postmenopausal; vaginal atrophy
- Replies: 0
- Forum: HRT in Women

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038