high sbhg

  1. S

    High estradiol and SHBG 10wks into TRT (was high on enclomiphene too) - long winded post sorry.

    I was brought here after listening to Nelson on Dr. Lyons podcast, man what a story and journey! 48M, 5'6" 160lbs. I lost 90lbs 25 years ago and have kept in shape ever since. I workout daily, love being in the gym, but never truly felt optimized. This last year or two I made it a goal to...
  2. F

    About to start TRT - should I?

    First of all hi! I've been reading and reading, absorbing everything I can from the very knowledgeable membership here. Phenomenal resource. For years now, I'd guess 7 or 8, I haven't felt myself at all. Currently 46, started a gradual decline in my late 30s. Symptoms include brain fog...
  3. R

    High SHBG and Free T

    My last three labs going back nine months all show my SHBG and free testosterone levels as high. The latest results showed 105.6 nmol/L SHBG and free testosterone of 45.9 pg/mL. I understand both being high is unusual. Has anyone else experienced this? Does anyone know what can possibly cause...
  4. J

    High SBHG, diet and low libido.

    I tested for low T at the beginning of the year. TT was 425 and FT was low at 6.3 (range 6.8-21.5). I did a full hormone panel in May before going on TRT and everything came back normal except my SBHG was high 95 (range 16.5-55). This was the first time I ever tested SBHG. I started treatment...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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