Hepcidin Mimetic

https://dailynews.ascopubs.org/do/hepcidin-modulation-polycythemia-vera-current-landscape-and-next-steps Conclusion Overall, methods to exogenously or endogenously increase hepcidin levels represent a novel mechanism to eliminate the need for therapeutic phlebotomy in patients with PV and...

* The most common treatment-emergent adverse events in the rusfertide arm were localized injection-site reactions (55.9%) and anemia (15.9%), which were consistent with the drug’s administration route and mechanism of action. * “Polycythemia vera represents a unique situation, where you...

Treatment guidelines in polycythemia vera currently recommend maintaining hematocrit below 45%, with a higher threshold for men vs women. https://www.ajmc.com/view/understanding-hematocrit-thresholds-in-polycythemia-vera-treatment In early March, The American Journal of Managed Care® spoke with...

Polycythemia vera is a classic myeloproliferative neoplasm and a chronic type of leukemia, which often leads to overproduction of various blood cells. Summary: Managing Polycythemia Vera to Reduce Risks and Improve Lives Polycythemia vera (PV) is a chronic myeloproliferative neoplasm-a type...

New Treatment Could End the Phlebotomy Cycle for Men with High Hematocrit If you're a man on testosterone replacement therapy (TRT) who's been told you need regular blood draws to manage your hematocrit levels, a breakthrough treatment currently in clinical trials could change everything. Recent...