first-generation phosphodiesterase 5 inhibitors

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  1. madman

    The first‐generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue

    ABSTRACT Background: Erectile dysfunction (ED) is a relatively frequent disease that negatively impacts the overall quality of life, well-being, and relationships. Although the use of phosphodiesterase 5 inhibitors (PDE5is) has revolutionized the treatment of ED, a high percentage of ED...
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