estradiol; lc-ms/ms; cobas i 601 analyzer

E2 Infinity and Beyond: Advancing Estradiol Testing with the Cobas i 601 Analyzer

MSACL 2025 Abstract Matthew R Chappell (1), Meghan N Bradley (1), Matthew L Crawford (1), Sven Groesgen (2), Philippe Metz (2), Russell P Grant (1) (1) Center for Esoteric Testing, Labcorp, Burlington NC 27215, (2) Roche Diagnostics GmbH, Mannheim, Germany Abstract INTRODUCTION The...
- madman
- Thread
- Oct 1, 2025
- estradiol; lc-ms/ms; cobas i 601 analyzer
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- Forum: Blood Test Discussion

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038