estradiol bone

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Could my low E2 (~10.0) have caused my herniated disc?

At only 34, I’ve somehow herniated a disc in my cervical spine. This hasn’t happened before, until I stopped TRT and I’ve been doing an unsuccessful restart. Total T at 225, E2 at 10.0. Is this low E2 low enough to cause bad inflammation or loss of cartilage to the point one will slip a disc...
- JCUSN
- Thread
- Aug 14, 2018
- bone healing estradiol estradiol bone
- Replies: 3
- Forum: Testosterone Basics & Questions
SHBG level may indicate risk for vertebral fractures in older men

Peggy M. Cawthon, PhD, MPH, of California Pacific Medical Center Research Institute in San Francisco, and colleagues analyzed data from 1,463 men aged at least 65 years participating in the osteoporotic fractures in men (MrOS) study who had been randomly selected for sex hormone measurements...
- Nelson Vergel
- Thread
- Jan 18, 2016
- Replies: 0
- Forum: Testosterone Side Effect Management
Estradiol of over 27 pg/mL protects bones in HIV+ people

Santi D, Madeo B, Carli F, et al. Serum total estradiol, but not testosterone is associated with reduced bone mineral density (BMD) in HIV-infected men: a cross-sectional, observational study. Osteoporos Int. http://www.ncbi.nlm.nih.gov/pubmed/26510848 By investigating the relationship...
- Nelson Vergel
- Thread
- Oct 30, 2015
- Replies: 2
- Forum: Testosterone Side Effect Management

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038