ed; diabetes mellitus; pdei; drug therapy

Changing Landscape of ED: Shift in Risk Factors and Presentation Patterns

https://academic.oup.com/jsm/article/21/Supplement_1/qdae001.228/7600739 Abstract Introduction Roughly 52% of men over the age of 40 have ED. However, our understanding of ED risk factors is constantly evolving. Objective The aim of this study is to provide a contemporary update of risk...
- madman
- Thread
- Feb 17, 2024
- ed; diabetes mellitus; pdei; drug therapy
- Replies: 0
- Forum: When TRT Is Not Enough (ED, Libido, & More)
Management of ED in men with diabetes mellitus unresponsive to PDE5i

ABSTRACT Introduction. Erectile dysfunction (ED) is associated with diabetes mellitus with an estimated prevalence of 52.5% in the diabetic population. The first-line therapy for ED is phosphodiesterase type 5 inhibitors (PDE5i), but data suggest that diabetic men may be less responsive than...
- madman
- Thread
- Aug 6, 2022
- ed; diabetes mellitus; pdei; drug therapy
- Replies: 5
- Forum: When TRT Is Not Enough (ED, Libido, & More)

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038