delayed puberty; hormone therapy

Curated By Nelson Vergel | ExcelMale.com | Updated April 2026 Key Takeaways • Age 14 is the medical deadline for boys, not a suggestion. If a boy has not reached a testicular volume of 4 ml by age 14, it is time to see a pediatric endocrinologist, not to keep waiting. • Most...

Abstract Delayed puberty (DP) defines retardation of onset/progression of sexual maturation beyond the expected age from either a lack/delay of the hypothalamic-pituitary-gonadal axis activation or a gonadal failure. DP usually gives rise to concern and uncertainty in patients and their...