corpus spongiosum

B
Looking for advice regarding trimix use

Hi, Hoping some of the other members here will be able to help. Short overview, I'm 45, been dealing with ED and loss of libido for 12 years. Done all the tests, had TRT several times in every form, no change. Viagra and Cialis did not work, pumps and rings only minimally with much discomfort...
- bcl79
- Thread
- Jan 27, 2025
- corpus spongiosum intracavernosal injectables trimix
- Replies: 1
- Forum: When TRT Is Not Enough (ED, Libido, & More)
A
First time use of Trimix yesterday

Hi, all. For the first time yesterday, I injected Trimix at the Doctor's office, a .05mL dose, and it worked great. One thing I noticed though, was that the corpus spongiosum, the spongy tissue that surrounds the urethra, did NOT seem to get hard in the least. Is this normal? Not worried...
- ah76
- Thread
- Nov 6, 2021
- corpus spongiosum
- Replies: 9
- Forum: When TRT Is Not Enough (ED, Libido, & More)

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038