apathy

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TRT, Weakness, Low Energy, and Dopamine?

Sorry in advance for the long post. I want to be thorough. I have been on TRT for 8 weeks through Defy. Defy says my recent follw-up labs are perfect. I am experiencing no libido, poor sexual response, no drive or motivation, poor mood (apathy or emotional flatness), general weakness, and lack...
- Dasein88
- Thread
- Jan 27, 2019
- apathy dopamime dr saya fatigue nelson vergel no libido trt weakness
- Replies: 80
- Forum: Testosterone Basics & Questions
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Estrogen crash causing permanent apathy/lethargy - by destroying your dopamine neurons?

Ive been on trt for 2 years now and had a estrogen crash this fall. From that point on I've been trying to redial my Ai protocol, and at the moment, im at a point where i've decided to ditch my arimidex completely. One of the thing that is worrying me is the fact that I cant seem to shake of...
- simeoni
- Thread
- Nov 26, 2016
- Replies: 25
- Forum: Testosterone Side Effect Management

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038