androgen receptor

  1. T

    Understanding free androgen Index

    Does anyone understand the implications of having a very high level of androgens despite being on a moderate dose of TRT. I’ve struggled for years to get “dialled” in. Mostly libido / ED I’m not one for chasing numbers per say but given all the variables, getting things into range is at least...
  2. T

    Great articles and discussion on terminology ("anabolic steroids" don't really exist)

    https://forums.t-nation.com/t/what-is-trt-and-what-is-not-trt/269828/807 https://forums.t-nation.com/t/what-is-trt-and-what-is-not-trt/269828/811 https://forums.t-nation.com/t/what-is-trt-and-what-is-not-trt/269828/777 No such thing as anabolic steroids or AAS. Technically correct term is...
  3. B

    Can TRT reduce sensitivity of androgen receptors?

    Is this possible or does this happen? Naturally the body frequently fluctuates hormone levels, and in TRT we have a constant steady supply and also a lot of us are a slight bit higher than we would be naturally. I was wondering if anyone with some knowledge on androgen receptor sensitivity and...
  4. 3

    Androgen Receptor Health Assessment

    Is it possible to test/assess the health of one's androgen receptors? I am just curious if there are tests that will predict the efficacy of TRT and/or determine the timeline of expected benefits. I would imagine Thyroid (TSH, T3, T4) is obvious. What else can be tested to determine AR health?
  5. M

    Possible Role of Androgen Receptor in Various Cancers (not just prostate)

    Have you seen this study Androgen receptors beyond prostate cancer: an old marker as a new target Javier Munoz, Jennifer J. Wheler, and Razelle Kurzrock Abstract Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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