allopregnanolone; neurosteroids; stress

DEEP DIVE: Strategies to Increase Allopregnanolone A Comprehensive Review for Mental Health Support 1. What is Allopregnanolone? Allopregnanolone (ALLO) is a neurosteroid synthesized from progesterone that acts as a potent positive allosteric modulator of GABA-A receptors. [1,2] Its potency at...

Allopregnanolone: Regenerative therapeutic to restore neurological health (2023) Gerson D. Hernandez, Roberta D. Brinton ABSTRACT Chronic stress has been proposed as a driver of altered brain structure and function, including the pathogenesis of neurodegenerative diseases, and a driver of...