Adverse Events

  1. madman

    CYP2D6 Genetic Variants Influence Hormonal and Spermatic Responses to Enclomiphene in Male Infertility Therapy

    * Univariate analysis showed that poor metabolizers had the greatest improvements in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and sperm concentration (Figures 1 and 2, p<0.05). There was no statistical difference in testosterone level. Multivariate linear regression...
  2. madman

    The Testosterone-Visceral Fat Connection: How Declining Levels and Exercise Shape Abdominal Health

    * Our findings indicate that a decline in testosterone levels is associated with increased body weight, BMI, waist circumference, and visceral fat, as well as reduced adiponectin levels. Furthermore, regular exercise appears to play a protective role in preventing testosterone decline...
  3. madman

    Restoring Fertility: The Role of hCG in Reversing Sperm Suppression from Non-Prescribed Androgens

    * The hCG treatment typically involved Ovitrelle, a single-dose injection pen containing 250 mcg of recombinant hCG, equivalent to 6,500 IU, which could be administered in multiple smaller doses (increments of 10 mcg = 260 IU). The standard treatment protocol consisted of three injections of 520...
  4. madman

    THE HISTORY OF PENILE GIRTH AUGMENTATION

    INTRODUCTION AND OBJECTIVE Penile appearance is a source of anxiety among men and has led to the development of diverse penile enhancement approaches. The goal of this study was to examine the history of penile girth enhancement procedures. METHODS Peer-reviewed literature in PubMed and...
  5. madman

    ENCLOMIPHENE VS. CLOMIPHENE: SAFETY AND TESTOSTERONE LEVELS IN HYPOGONADAL MEN

    INTRODUCTION AND OBJECTIVE Both clomiphene citrate and its isomer, enclomiphene, have become increasingly widespread within urologic practice; thus, understanding these medications' comparative benefits and risks is crucial for optimizing treatment decisions and providing improved therapeutic...
  6. madman

    A PHARMACOVIGILANCE STUDY OF hCG -ASSOCIATED ADVERSE EVENTS IN MALES

    INTRODUCTION AND OBJECTIVE Human chorionic gonadotropin (hCG) is an exogenous analog of luteinizing hormone (LH). The only FDA-approved indication for males is to treat hypogonadotropic hypogonadism and cryptorchidism. hCG is used off-label to treat other conditions, including hypogonadism with...
  7. madman

    SARM use and related adverse events including drug‑induced liver injury

    Abstract Purpose Selective androgen receptor modulators (SARMs) have demonstrated agonist activity on the androgen receptor in various tissues, stimulating muscle mass growth and improving bone reconstruction. Despite being in clinical trials, none has been approved by the Food and Drug...

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