advanced pca; transdermal estradiol; lh-rh

Talking Estradiol (E2) for Recurrent/Advanced Prostate Cancer

Estrogen in its various forms has long been used as a primary and secondary means of managing prostate cancer. Primarily it can be used in place of an LHRH ADT drug. In its secondary capacity, it can be employed in addition to an LHRH drug to help men cope with side effects arising from lack of...
- madman
- Thread
- Nov 9, 2024
- advanced pca; transdermal estradiol; lh-rh
- Replies: 2
- Forum: Prostate Related Issues
Transdermal estradiol for androgen suppression in locally advanced prostate cancer

Transdermal estradiol for androgen suppression in locally advanced prostate cancer Duncan Gilbert, MA, MRCP, FRCR, PhD, University College London, London, UK, discusses the Phase III PATCH trial (ISRCTN70406718), which investigated transdermal estradiol as an alternative to traditional...
- madman
- Thread
- Nov 8, 2024
- advanced pca; transdermal estradiol; lh-rh
- Replies: 4
- Forum: Prostate Related Issues

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038