adrenal insufficiency

  1. Gianluca

    Zinc acutely and temporarily inhibits adrenal cortisol secretion in humans. A preliminary report

    Abstract Hypo- and hyperzincemia has been reported to cause alterations in the adrenal secretion. To determine the acute effect of zinc on cortisol levels, we studied 27 normal individuals of both sexes aged 20-27 y after a 12-h fast. The tests were initiated at 7:00 AM when an antecubital vein...
  2. lemonflavor

    Case Challenge: Chronic Opioid Use Causing Adrenal Insufficiency

    Case Challenge: Chronic Opioid Use Causing Adrenal Insufficiency Sickle cell anemia patient develops opioid-induced endocrinopathy while on chronic opioid therapy. I found this interesting even without the opioid component. Lab numbers are included in the article. She was either at the low end...
  3. jger242

    jger242 labs - questions

    I have several different problems. Any assistance is appreciated. 1. Low average daily body temp (97.1 average daily temp) occassionally rises to 98.0 - 98.5 after training. 2. Inability to lose weight. I have tried several different plans: increased activity (cardio, etc) reduced calories...
  4. Nelson Vergel

    Utility of the low-dose short Synacthen test in diagnosis of adrenal insufficiency

    Has anyone used the Synacthen test to get diagnosed with adrenal insufficiency (low cortisol output)? The short Synacthen [tetracosactrin i.e. synthetic adrenocorticotropic hormone (ACTH) ] test is routinely used to diagnose adrenal insufficiency, both primary and secondary (i.e. due to...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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