acth

* Aldosterone, the principal mineralocorticoid, is exclusively synthesized in the glomerular zone of the adrenal cortex. Its primary function is to maintain water and electrolyte balance and regulate blood pressure. * The regulation of its production is classified as acute, dependent on the...

All the literature I've read suggests that exogenous testosterone tends to have a suppressive effect on adrenal (and potentially thyroid) activity. It makes sense -- if your body has enough hormones, you won't be generating as much pregnenolone -> other hormones (including cortisol downstream)...

A frequent cause of high blood pressure and water retention is when levels of certain hormones in the body are unbalanced or functioning poorly. The hormones that are frequently at fault are secreted by the kidneys and the pituitary or adrenal glands. They are called aldosterone, ACTH, and renin...