acne; topical retinoids; management/treatment

An update on the pharmacological management of acne vulgaris

* Four main interrelated pathogenic factors, that act synergistically in a complex manner are involved in the development of acne lesions: 1. Increased sebum production due to androgen-driven sebaceous gland hyperplasia; 2. Hyperkeratinization of the follicular epithelium due to abnormal...
- madman
- Thread
- Nov 7, 2024
- acne; topical retinoids; management/treatment
- Replies: 0
- Forum: Testosterone Side Effect Management
Management of Acne Vulgaris With Trifarotene

Management of Acne Vulgaris With Trifarotene (2023) Jerry Tan, MD, Rajeev Chavda, MD, Hilary Baldwin, MD, and Brigitte Dreno, MD, PhD Abstract Topical retinoids have an essential role in the treatment of acne. Trifarotene, a topical retinoid selective for retinoic acid receptor (RAR) γ, is...
- madman
- Thread
- Mar 18, 2023
- acne; topical retinoids; management/treatment
- Replies: 6
- Forum: Testosterone Side Effect Management

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038