5ari's

Finasteride and dutasteride, synthetic 5α-reductase inhibitors (5ARIs) are recommended in many guidelines for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms and alopecia despite a variety of side effects like sexual, neurological, psychiatric, endocrinological...

What’s New in Therapy for Male Androgenetic Alopecia? (2022) David Saceda‑Corralo · Miguel Domínguez‑Santas · Sergio Vañó‑Galván · Ramon Grimalt Abstract Male androgenetic alopecia is a common condition and represents a major concern for patients who experience this condition. While there are...

Introduction: Five-alpha reductase (5-AR) deficiency was first identified by Imperato-McGinley and Walsh as the cause of pseudohermaphroditism in two separate studies. The discoveries led to the development of finasteride (inhibitor of type 2 isoenzyme of 5-AR) and dutasteride (inhibitor of type...