5a-r metabolites testosterone; nervous system

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  1. madman

    Synthesis and Actions of 5a-R Metabolites of T in the Nervous System

    Abstract Neuroactive testosterone metabolites synthesized by enzymes 5a-reductase and 3a/3b-hydroxysteroid oxidoreductase are critical physiological modulators of the central nervous system (CNS) function. Indeed, as discussed in this review, they exert a variety of effects on myelination...
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