1. #1
    Super Moderator Nelson Vergel's Avatar
    Join Date
    Sep 2013
    Houston, Texas, United States

    Hypogonadal men with psoriasis benefit from long-term testosterone replacement therapy

    Andrologia. 2016 Apr;48(3):341-6. doi: 10.1111/and.12452. Epub 2015 Jul 16.

    Hypogonadal men with psoriasis benefit from long-term testosterone replacement therapy - a series of 15 case reports.

    Saad F1,2, Haider A3, Gooren L4.

    Author information

    1Global Medical Affairs Andrology, Bayer Pharma AG, Berlin, Germany.
    2Gulf Medical University, Ajman, UAE.
    3Private Urology Practice, Bremerhaven, Germany.
    4Department of Internal Medicine, Endocrine Section, VU medical Center, Amsterdam, The Netherlands.


    Psoriasis is increasingly recognised as a skin disease with far-reaching systemic effects, associated with a high prevalence of comorbid disease such as cardiometabolic dysfunction, shifting the focus from a single organ disease confined to the skin to a systemic inflammatory condition. Chronic and systemic inflammation plays a major role in the development of these diseases, and there are striking similarities between the molecular and inflammatory pathways in psoriasis and atherosclerosis. In a single-centre, cumulative, prospective registry study of 347 hypogonadal men (total testosterone ≤12.1 nmol l(-1) ), fifteen men with psoriasis could be studied. Upon testosterone administration, the skin disease improved considerably. Scores on the Psoriasis Area and Severity Index and Physician Global Assessment for Psoriasis showed significant improvement for the first 24 months. Thereafter, these improvements were sustained. Upon testosterone treatment, C-reactive protein declined significantly. There were significant improvements of obesity and of lipid profiles. Adipose tissue is now regarded as a source of inflammatory factors. These preliminary results deserve to be studied in a specifically designed study to investigate the effects of testosterone on psoriasis and its associated immunopathology.

    Author of Testosterone: A Man's Guide & Built to Survive

    Please no private messages. I answer questions on the forum for all to benefit.

  2. # ADS
    Purchase From Our Affiliates
    Join Date
    Houston, TX
    Help Excelmale


  3. #2
    Yet another autoimmune condition that favourably responds to TRT. Of course, the popular press will ignore this in favour of inaccurate, scare-mongering stories that paint androgen therapy as a dangerous and immoral activity.

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Similar Threads

  1. Some Results of Long Term Testosterone Therapy
    By Jinzang in forum Testosterone- Miscellaneous Studies
    Replies: 2
    Last Post: 12-12-2016, 12:13 PM
  2. Long-term Testosterone Beneficial in Hypogonadal Men
    By Jinzang in forum Testosterone- Miscellaneous Studies
    Replies: 1
    Last Post: 11-11-2016, 05:10 PM
  3. Long term health effects of testosterone replacement
    By tmix in forum Testosterone Basics & Questions
    Replies: 6
    Last Post: 09-22-2016, 10:21 AM
  4. Hypogonadal men with psoriasis benefit from testosterone
    By Nelson Vergel in forum Testosterone- Miscellaneous Studies
    Replies: 0
    Last Post: 07-29-2015, 11:28 AM
  5. Living like Mr. Universe may not benefit you long-term
    By Donnie Moreland in forum Health & Wellness
    Replies: 0
    Last Post: 01-08-2014, 07:27 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts