Transdermal Tesosterone - Serum Concentration Timeline

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S1W

Well-Known Member
I've done a bit of searching here and elsewhere, and can't seem to find the information I'm looking for. I'm curious about what the timeline for serum testosterone concentration looks like for users of compounded creams, etc. I found a very basic graphic for Testim and a few other randoms, but none were very detailed.

It seems that serum concentrations peak anywhere between 2 and 6 hours after application, and remain elevated for up to 16 hours.

My question would be: What happens in those later hours? Do levels drop BELOW pre-TRT baseline for say hours 16-24, or are they still somewhat elevated above pre-TRT baseline once a user is several weeks/months into a daily transdermal protocol?
 
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madman

Super Moderator
I've done a bit of searching here and elsewhere, and can't seem to find the information I'm looking for. I'm curious about what the timeline for serum testosterone concentration looks like for users of compounded creams, etc. I found a very basic graphic for Testim and a few other randoms, but none were very detailed.

It seems that serum concentrations peak anywhere between 2 and 6 hours after application, and remain elevated for up to 16 hours.

My question would be: What happens in those later hours? Do levels drop BELOW pre-TRT baseline for say hours 16-24, or are they still somewhat elevated above pre-TRT baseline once a user is several weeks/months into a daily transdermal protocol?

https://academic.oup.com/jcem/article/85/12/4500/2852336
 
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