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My urologist seems to just order it for $30/each directly from Empower? They claim to have done this for other pts? I don't actually know anything about Defy. Re: @granger lol yeah probably. Interesting that you had higher residual levels like that - I still think the nasal route (nevermind...

@BigBeard411 Did you ever try Empower's formulary version? The adverse effects of clomiphene/enclomiphene seem to also be somewhat underrated by physicians in my view (again I assume because as a % of treated population they are still very small), but there are definite visual field...

@BigBeard411 Yes I concur Natesto is just unfortunately dead. 1. Most physicians claim testosterone doesn't cause tachycardia, palpitations, etc. but that seems directly AT ODDS with anecdotal reports on this forum alone, as well as online. In fact they seem more than common enough to...

Hi Granger - absolutely fascinating, thank you for confirming you had similar symptoms. [I'll mention as an aside I appreciate all your input - yourself and a few other people on this forum are clearly some combination of higher IQ, autistic, and/or more observant than 95% of the people who...

So no real update PER SE... BUT I did wind up having a pretty adverse reaction to something. Am taking Minoxidil (PO 2.5mg, 1.5yrs) and Natesto 2x/day for 3 weeks now almost finished with first vial (which has crystals). I also - stupidly and randomly without much thought - took 2 tablets of...

My point was basically my guess is the formulary compounding method is simpler and not refined, though this could mean less crystallization - this is why they use so many different binders and solvents, whereas Natesto's manufacturing process may be more labor intensive to dissolve the hormone...

Interesting that you have so many vials! I have only 1 out of 6 that was mostly clean - 1-2 visible crystals, this is the one I'm trial-using right now. The 'gentleness' of Natesto in terms of its rapid half-life and relatively low dose I believe makes determining the dosing (on a physiology...

Hey - yes I had noticed you were a very active Natesto poster on here! I've also noted though people DO report many instances of suspecting Natesto wasn't being dosed correctly or evenly? We also know Natesto did recall vials for this reason. Finally, it's of course well known that IV...

Agreed - frankly as this is the very first time I have ever used it, I'm more just trying to figure out whether it's a time issue (I need to use it for several weeks) or its the crystallization issue. I 100% am convinced at this point that these crystals are not normal - see photos below. 6...

Despite protestations from pharmacists - upon seeing the crystals they agreed it seemed possible but were incredulous that so many different lots could all have the issue... and that no other patients had ever reported it (also noting Natesto isn't that popular and they're not familiar with it...

I take your points - I've not experienced any issues with the applicator not depressing though. I may ask the pharmacy to try to exchange the unopened vials from the batch - one of them is riddled with crystals - I'm test/using the one that has the least but its obviously just not an optimal...

Wanted to update on this. I obtained a second batch of Natesto (Dec 2025 expiry) and indeed the vials ALSO have inclusion crystals in them (thank you Zalemax for posting that photo above seemingly confirming that these inclusions are NOT present in all vials and do not seem to be a normal...

And yes, sorry didn't mean to be repeating what you said you mostly commented about this phenomenon already.

Update on this: two pharmacies and a physician noted they have never had any patients complain about crystallization with Natesto gel (they note its possible of course though). Acerus is basically unreachable/a shell company it seems they don't communicate with anyone (surprising the drug gets...

Surprised you're the ONLY poster who mentioned this. 100% new to TRT and after 3 days realized Natesto was completely ineffective, zero physical or psychological changes. At first I thought maybe it was from poor absorption - used a cotton swab to better layer the gel in the nares, no effect...